Biotech & Biopharma Screening
The biotech and biopharmaceutical industry is faced with increasing prices and stricter regulations. Additionally, there is an industrial push to reduce costs and maintain biosafety for both lab staff and patients, while products are made more specific to molecular disease targets or even tailored for personalised medicine. This results in a number of challenges regarding product development and flexibility of systems, with procedure documentation and sample tracking as critical assets.
Automated high throughput screening on cell culture assays allows for hit discovery with functional endpoints on a wide variety of diseases from oncology, immunology, cardiology, metabolism and pathogenic infections. A compact platform provides a cost-effective way of accessing high throughput screening, also in the appropriate biosafety conditions for pathogen toxicity assays.
Also in production and QC solutions were developed such as aseptic filling of molecular reagents.
Some Realizations
Caps-It & Mini-Caps
High throughput system for cell assays on live pathogens of high biosafety risk.
The Caps_It system contains redundant customized subsystems to assure safe and efficient plate handling. This includes: incubators, liquid handlers, confocal high content imagers, multimode plate readers, plate washers, a dark plate store and integrated liquid waste handling.
Your benefits:
- High throughput cell based assays
- Compact cost effective P3 lab solution
- Operator and lab safety
- Reliable and traceable 24/7 operation
- 21 CFR part 11 option.
The Caps-iT and MiniCaps system are integrated in an autonomous isolator system scalable up to P3 level biosafety containment. You can operate safely with high risk pathogens while working in a P2 lab.
See also: https://rega.kuleuven.be/cmt/capsit, a proven solution with many peer reviewed publications in high ranked journals.
Detailed description MiniCaps | Read white paper
Related project: Automated Flask Cell Culture
Automated high precision filling of vial batches in sterile conditions
Are you looking for a solution for precise and reliable small volume vial filling for your production line that only requires attention of the operators twice a day? Dealing with volumes between 100 µl and 2 ml, need ful data tracking? This filler unit may offer a quick solution to your needs.
Automated Labeller and Dispenser
The automated system concerns a lab application to distribute liquid aliquots in microcentrifuge tubes of 0,5ml or 1,5 ml. Liquid transfer is performed under laminar flow. The system is able to provide individual tubes from a bulk feed, controlled liquid transfer on a balance and labelling of 120 samples per hour. A vibration hopper with capacity for 1200 tubes feeds closed microcentrifuge tubes to a vertical lift that brings the tubes within reach of the XYZ robot. New tubes coming from the vibrator are capped. The labelled tubes first get decapped, receive the aliquot volume, and afterwards capped again. Prepared tubes are exported in 13x13cm trays with 100 positions.